Nexium vs Pepto-Bismol:Which is more popular?
In September 2026, Pepto-Bismol had more branded searches than Nexium among heartburn and digestive brands in the United States. Pepto-Bismol had about 301,000 branded searches, while Nexium had 90,500. Pepto-Bismol made up 31.1% of all heartburn and digestive brand searches we track, and Nexium accounted for 9.3%. When we asked ChatGPT and Google AI Overviews about heartburn and digestive brands, Pepto-Bismol appeared in two of the five answers and Nexium in one.
Who do people search for more?
Pepto-Bismol, about 3 searches for every 1 for Nexium
Who does AI mention more?
Pepto-Bismol, mentioned in 2 of 5 answers, Nexium in 1
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Top heartburn and digestive brands in ChatGPT and Google AI Overviews
In three ChatGPT questions and two Google AI Overviews, Pepto-Bismol was mentioned in two out of five: in one of the three ChatGPT answers and in one of the two Google AI Overviews. Nexium was mentioned in one out of five: not in any of the three ChatGPT answers, but in one of the two Google AI Overviews.
Most recommended by AI
Brands get a higher ranking if they are mentioned earlier in the answers.
Tums1st
Pepcid2nd
Prilosec OTC3rd
Pepto-Bismol4th
Gaviscon5th
Nexium6th
Mentioned by AI
Each dot is one answer, filled in when that answer mentions the brand.
Tums5 of 5Named in 3 of 3 ChatGPT answersNamed in 2 of 2 Google answers
Pepcid3 of 5Named in 2 of 3 ChatGPT answersNamed in 1 of 2 Google answers
Prilosec OTC3 of 5Named in 2 of 3 ChatGPT answersNamed in 1 of 2 Google answers
Pepto-Bismol2 of 5Named in 1 of 3 ChatGPT answersNamed in 1 of 2 Google answers
Nexium1 of 5Named in 0 of 3 ChatGPT answersNamed in 1 of 2 Google answers
Gaviscon1 of 5Named in 1 of 3 ChatGPT answersNamed in 0 of 2 Google answers
See every answer about heartburn and digestive brands
5 answers
Asked ChatGPT
“What's the best medicine for heartburn?”
Asked ChatGPT
“What's the best antacid?”
Asked ChatGPT
“What should I take for an upset stomach?”
Searched Google, AI Overview
“heartburn medicine”
Searched Google, AI Overview
“antacid”
- 1
Tums
- 1
Brands are shown in the order each answer named them. The survey took place in United States on October 27, 2026.
Is Nexium or Pepto-Bismol more popular in search?
This chart shows how often people search Google for Nexium and Pepto-Bismol by name. Each line represents a brand's share of searches for all six heartburn and digestive brands we track, month by month, from searches in United States.
Share of searches by month for Pepto-Bismol, Nexium. The figures are in the table below the chart.
View monthly share of searches table
| Month | Pepto-Bismol | Pepcid | Prilosec OTC | Tums | Nexium | Gaviscon |
|---|---|---|---|---|---|---|
| Oct 2025 | 31.6% | 21.1% | 17.3% | 14.2% | 9.5% | 6.3% |
| Nov 2025 | 28.7% | 23.5% | 15.8% | 15.8% | 10.6% | 5.8% |
| Dec 2025 | 32.1% | 21.5% | 14.4% | 14.4% | 9.7% | 7.9% |
| Jan 2026 | 31.6% | 21.1% | 17.3% | 14.2% | 9.5% | 6.3% |
| Feb 2026 | 33.5% | 22.4% | 15% | 12.2% | 10.1% | 6.7% |
| Mar 2026 | 30.2% | 24.6% | 16.5% | 13.5% | 9.1% | 6.1% |
| Apr 2026 | 31.1% | 25.4% | 13.9% | 13.9% | 9.3% | 6.3% |
| May 2026 | 31.1% | 25.4% | 13.9% | 13.9% | 9.3% | 6.3% |
| Jun 2026 | 26.9% | 26.9% | 14.8% | 14.8% | 9.9% | 6.6% |
| Jul 2026 | 31.6% | 25.9% | 14.2% | 14.2% | 7.8% | 6.4% |
| Aug 2026 | 31.1% | 25.4% | 13.9% | 13.9% | 9.3% | 6.3% |
| Sep 2026 | 31.1% | 25.4% | 13.9% | 13.9% | 9.3% | 6.3% |
How has the Nexium and Pepto-Bismol comparison changed over the last 12 months?
3 findings
- Pepto-Bismol was ahead of Nexium in every measured month of the 12 months ending September 2026.
- Across the 12 months ending September 2026, Nexium’s share of searches among heartburn and digestive brands in the United States moved from 9.5% to 9.3%, and its estimated monthly branded searches held steady at 90.5K.
- Across the 12 months ending September 2026, Pepto-Bismol’s share of searches among heartburn and digestive brands in the United States moved from 31.6% to 31.1%, and its estimated monthly branded searches held steady at 301K.
How did search popularity change for United States heartburn and digestive brands in September 2026?
0 changes
Neither Nexium nor Pepto-Bismol moved beyond provider rounding among heartburn and digestive brands in September 2026.
How are branded searches counted?
2 search terms
Brandwave collects information about searches that people make online using Nexium’s and Pepto-Bismol’s names. When viewed over time, estimated search volumes for these branded terms can be used to understand whether interest in the brands is growing, holding steady, or fading.
Nexium
1 branded search term
- nexium
Pepto-Bismol
1 branded search term
- pepto bismol
Other head-to-heads among heartburn and digestive brands

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