Nexium vs Pepcid:Which is more popular?
In September 2026, Pepcid had more branded searches than Nexium among heartburn and digestive brands in the United States. Pepcid had about 246,000 branded searches, while Nexium had 90,500. Pepcid made up 25.4% of all heartburn and digestive brand searches we track, and Nexium accounted for 9.3%. When we asked ChatGPT and Google AI Overviews about heartburn and digestive brands, Pepcid appeared in three of the five answers and Nexium in one. Pepcid was mentioned before Nexium in every answer.
Who do people search for more?
Pepcid, about 3 searches for every 1 for Nexium
Who does AI mention more?
Pepcid, mentioned in 3 of 5 answers, Nexium in 1
Who does AI recommend more?
Pepcid, named ahead of Nexium in every answer
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Top heartburn and digestive brands in ChatGPT and Google AI Overviews
In three ChatGPT questions and two Google AI Overviews, Pepcid was mentioned in three out of five: in two of the three ChatGPT answers and in one of the two Google AI Overviews. Nexium was mentioned in one out of five: not in any of the three ChatGPT answers, but in one of the two Google AI Overviews. Pepcid was listed before Nexium in every answer.
Most recommended by AI
Brands get a higher ranking if they are mentioned earlier in the answers.
Tums1st
Pepcid2nd
Prilosec OTC3rd
Pepto-Bismol4th
Gaviscon5th
Nexium6th
Mentioned by AI
Each dot is one answer, filled in when that answer mentions the brand.
Tums5 of 5Named in 3 of 3 ChatGPT answersNamed in 2 of 2 Google answers
Pepcid3 of 5Named in 2 of 3 ChatGPT answersNamed in 1 of 2 Google answers
Prilosec OTC3 of 5Named in 2 of 3 ChatGPT answersNamed in 1 of 2 Google answers
Pepto-Bismol2 of 5Named in 1 of 3 ChatGPT answersNamed in 1 of 2 Google answers
Nexium1 of 5Named in 0 of 3 ChatGPT answersNamed in 1 of 2 Google answers
Gaviscon1 of 5Named in 1 of 3 ChatGPT answersNamed in 0 of 2 Google answers
See every answer about heartburn and digestive brands
5 answers
Asked ChatGPT
“What's the best medicine for heartburn?”
Asked ChatGPT
“What's the best antacid?”
Asked ChatGPT
“What should I take for an upset stomach?”
Searched Google, AI Overview
“heartburn medicine”
Searched Google, AI Overview
“antacid”
- 1
Tums
- 1
Brands are shown in the order each answer named them. The survey took place in United States on October 27, 2026.
Is Nexium or Pepcid more popular in search?
This chart shows how often people search Google for Nexium and Pepcid by name. Each line represents a brand's share of searches for all six heartburn and digestive brands we track, month by month, from searches in United States.
Share of searches by month for Pepcid, Nexium. The figures are in the table below the chart.
View monthly share of searches table
| Month | Pepto-Bismol | Pepcid | Prilosec OTC | Tums | Nexium | Gaviscon |
|---|---|---|---|---|---|---|
| Oct 2025 | 31.6% | 21.1% | 17.3% | 14.2% | 9.5% | 6.3% |
| Nov 2025 | 28.7% | 23.5% | 15.8% | 15.8% | 10.6% | 5.8% |
| Dec 2025 | 32.1% | 21.5% | 14.4% | 14.4% | 9.7% | 7.9% |
| Jan 2026 | 31.6% | 21.1% | 17.3% | 14.2% | 9.5% | 6.3% |
| Feb 2026 | 33.5% | 22.4% | 15% | 12.2% | 10.1% | 6.7% |
| Mar 2026 | 30.2% | 24.6% | 16.5% | 13.5% | 9.1% | 6.1% |
| Apr 2026 | 31.1% | 25.4% | 13.9% | 13.9% | 9.3% | 6.3% |
| May 2026 | 31.1% | 25.4% | 13.9% | 13.9% | 9.3% | 6.3% |
| Jun 2026 | 26.9% | 26.9% | 14.8% | 14.8% | 9.9% | 6.6% |
| Jul 2026 | 31.6% | 25.9% | 14.2% | 14.2% | 7.8% | 6.4% |
| Aug 2026 | 31.1% | 25.4% | 13.9% | 13.9% | 9.3% | 6.3% |
| Sep 2026 | 31.1% | 25.4% | 13.9% | 13.9% | 9.3% | 6.3% |
How has the Nexium and Pepcid comparison changed over the last 12 months?
3 findings
- Pepcid was ahead of Nexium in every measured month of the 12 months ending September 2026.
- Across the 12 months ending September 2026, Nexium’s share of searches among heartburn and digestive brands in the United States moved from 9.5% to 9.3%, and its estimated monthly branded searches held steady at 90.5K.
- Across the 12 months ending September 2026, Pepcid’s share of searches among heartburn and digestive brands in the United States moved from 21.1% to 25.4%, and its estimated monthly branded searches moved from 201K to 246K.
How did search popularity change for United States heartburn and digestive brands in September 2026?
1 change

Estimated monthly branded searches for Pepcid in the United States rose 22.4% over 12 measured months, from 201K to 246K in September 2026.
How are branded searches counted?
2 search terms
Brandwave collects information about searches that people make online using Nexium’s and Pepcid’s names. When viewed over time, estimated search volumes for these branded terms can be used to understand whether interest in the brands is growing, holding steady, or fading.
Other head-to-heads among heartburn and digestive brands

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