Brandwave

Difflam vs Tylenol:Which is more popular?

In September 2026, Tylenol had more branded searches than Difflam among cold and flu brands worldwide. Tylenol had about 1 million branded searches, while Difflam had 74,000. Tylenol made up 21.7% of all cold and flu brand searches we track, and Difflam accounted for 1.6%. When we asked ChatGPT and Google AI Overviews about cold and flu brands, Tylenol appeared in three of the five answers and Difflam in none.

Among cold and flu brands worldwide in September 2026

Who do people search for more?

Tylenol, about 14 searches for every 1 for Difflam

Tylenol 1M searchesDifflam 74K searches

Who does AI mention more?

Tylenol, mentioned in 3 of 5 answers, Difflam in 0

Tylenol in 3 of 5Difflam in 0 of 5

Who does AI recommend more?

Tylenol, the only one of the two named

Tylenol first in 3Difflam never named

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Top cold and flu brands in ChatGPT and Google AI Overviews

In three ChatGPT questions and two Google AI Overviews, Tylenol was mentioned in three out of five: in two of the three ChatGPT answers and in one of the two Google AI Overviews. Difflam did not appear in any of the five answers.

Most recommended by AI

Brands get a higher ranking if they are mentioned earlier in the answers.

  1. Mucinex1st
  2. DayQuil2nd
  3. NyQuil3rd
  4. Sudafed4th
  5. Tylenol5th
  6. Vicks6th
  7. Strepsils–
  8. Difflam–
  9. Coldrex–

Mentioned by AI

Each dot is one answer, filled in when that answer mentions the brand.

  • Mucinex4 of 5Named in 3 of 3 ChatGPT answersNamed in 1 of 2 Google answers
  • Tylenol3 of 5Named in 2 of 3 ChatGPT answersNamed in 1 of 2 Google answers
  • Sudafed3 of 5Named in 2 of 3 ChatGPT answersNamed in 1 of 2 Google answers
  • NyQuil3 of 5Named in 3 of 3 ChatGPT answersNamed in 0 of 2 Google answers
  • DayQuil3 of 5Named in 3 of 3 ChatGPT answersNamed in 0 of 2 Google answers
  • Vicks1 of 5Named in 1 of 3 ChatGPT answersNamed in 0 of 2 Google answers
  • Strepsils0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers
  • Difflam0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers
  • Coldrex0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers

See every answer about cold and flu brands

5 answers

Not named in any answer:

Brands are shown in the order each answer named them. The survey took place in the United States on October 20, 2026.

Is Difflam or Tylenol more popular in search?

This chart shows how often people search Google for Difflam and Tylenol by name. Each line represents a brand's share of searches for all nine cold and flu brands we track, month by month, from English-language searches worldwide.

Difflam and Tylenol among cold and flu brands worldwide, by month

Share of searches by month for Tylenol, Difflam. The figures are in the table below the chart.

View monthly share of searches table
MonthVicksTylenolStrepsilsMucinexSudafedNyQuilDayQuilDifflamColdrex
Oct 202526.9%28.9%15.8%8.7%8.7%4.7%3.2%1.7%1.4%
Nov 202524.5%25.4%17.1%11.4%9.4%6.3%3.4%1.5%1%
Dec 202526%18.6%15.3%15.3%10.2%6.9%4.6%1.7%1.4%
Jan 202626%22.7%15.3%12.5%10.2%6.8%3.7%1.4%1.4%
Feb 202625.3%22.1%14.9%12.2%12.2%6.7%3.7%1.6%1.3%
Mar 202624.2%22.9%15.4%12.6%12.6%5.6%3.8%1.7%1.1%
Apr 202622.3%25.9%17.4%11.6%11.6%5.2%3.5%1.6%0.86%
May 202623.7%23.1%18.9%12.7%10.3%5.7%3.1%1.7%0.76%
Jun 202626.2%25%20.4%9.1%9.1%5%2.7%1.8%0.55%
Jul 202626.2%25%20.4%9.1%9.1%5%2.7%1.8%0.55%
Aug 202625%26.8%18%9.8%9.8%5.4%2.9%1.6%0.59%
Sep 202624.8%21.7%17.9%12%9.8%6.5%4.4%1.6%1.3%

How has the Difflam and Tylenol comparison changed over the last 12 months?

3 findings
  • Tylenol was ahead of Difflam in every measured month of the 12 months ending September 2026.
  • Across the 12 months ending September 2026, Difflam’s share of searches among cold and flu brands worldwide moved from 1.7% to 1.6%, and its estimated monthly branded searches moved from 90.5K to 74K.
  • Across the 12 months ending September 2026, Tylenol’s share of searches among cold and flu brands worldwide moved from 28.9% to 21.7%, and its estimated monthly branded searches moved from 1.5M to 1M.

How did search popularity change for cold and flu brands worldwide in September 2026?

2 changes
  1. In September 2026, Tylenol lost share of searches among cold and flu brands worldwide, from 26.8% to 21.7%.

  2. Estimated monthly branded searches for Difflam worldwide fell 18.2% over 12 measured months, from 90.5K to 74K in September 2026.

How are branded searches counted?

2 search terms

Brandwave collects information about searches that people make online using Difflam’s and Tylenol’s names. When viewed over time, estimated search volumes for these branded terms can be used to understand whether interest in the brands is growing, holding steady, or fading.

Difflam

1 branded search term

  • difflam

Tylenol

1 branded search term

  • tylenol

How the Brand Demand Index is measured

Other head-to-heads among cold and flu brands

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