Brandwave

Benadryl vs Zyrtec:Which is more popular?

In September 2026, Benadryl had more branded searches than Zyrtec among allergy medicine brands in the United States. Benadryl had about 450,000 branded searches, while Zyrtec had 368,000. Benadryl made up 30.3% of all allergy medicine brand searches we track, and Zyrtec accounted for 24.7%. When we asked ChatGPT and Google AI Overviews about allergy medicine brands, Zyrtec appeared in four of the five answers and Benadryl in two. Zyrtec was mentioned before Benadryl in every answer that named either.

Among allergy medicine brands in the United States in September 2026

Who do people search for more?

Benadryl, about 22% more searches than Zyrtec

Benadryl 450K searchesZyrtec 368K searches

Who does AI mention more?

Zyrtec, mentioned in 4 of 5 answers, Benadryl in 2

Zyrtec in 4 of 5Benadryl in 2 of 5

Who does AI recommend more?

Zyrtec, named ahead of Benadryl in 4 of 4 answers

Zyrtec first in 4Benadryl never first

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Top allergy medicine brands in ChatGPT and Google AI Overviews

In three ChatGPT questions and two Google AI Overviews, Zyrtec was mentioned in four out of five: in two of the three ChatGPT answers and in both Google AI Overviews. Benadryl was mentioned in two out of five: not in any of the three ChatGPT answers, but in both Google AI Overviews. Zyrtec was listed before Benadryl in every answer that named either.

Most recommended by AI

Brands get a higher ranking if they are mentioned earlier in the answers.

  1. Allegra1st
  2. Claritin2nd
  3. Zyrtec3rd
  4. Flonase4th
  5. Nasacort5th
  6. Xyzal6th
  7. Benadryl7th

Mentioned by AI

Each dot is one answer, filled in when that answer mentions the brand.

  • Flonase5 of 5Named in 3 of 3 ChatGPT answersNamed in 2 of 2 Google answers
  • Zyrtec4 of 5Named in 2 of 3 ChatGPT answersNamed in 2 of 2 Google answers
  • Claritin4 of 5Named in 2 of 3 ChatGPT answersNamed in 2 of 2 Google answers
  • Allegra4 of 5Named in 2 of 3 ChatGPT answersNamed in 2 of 2 Google answers
  • Nasacort3 of 5Named in 1 of 3 ChatGPT answersNamed in 2 of 2 Google answers
  • Benadryl2 of 5Named in 0 of 3 ChatGPT answersNamed in 2 of 2 Google answers
  • Xyzal2 of 5Named in 0 of 3 ChatGPT answersNamed in 2 of 2 Google answers

See every answer about allergy medicine brands

5 answers

Brands are shown in the order each answer named them. The survey took place in United States on October 27, 2026.

Is Benadryl or Zyrtec more popular in search?

This chart shows how often people search Google for Benadryl and Zyrtec by name. Each line represents a brand's share of searches for all seven allergy medicine brands we track, month by month, from searches in United States.

Benadryl and Zyrtec among allergy medicine brands in the United States, by month

Share of searches by month for Benadryl, Zyrtec. The figures are in the table below the chart.

View monthly share of searches table
MonthBenadrylZyrtecFlonaseClaritinAllegraXyzalNasacort
Oct 202532.3%21.6%14.4%11.8%7.9%9.7%2.4%
Nov 202530.8%25.2%13.8%11.3%7.6%9.2%2.3%
Dec 202529.7%24.3%16.2%10.9%7.3%8.9%2.7%
Jan 202633%22%18%9.9%6.6%8.1%2.4%
Feb 202628%22.9%18.7%12.6%6.9%8.4%2.5%
Mar 202624.2%24.2%16.2%13.2%8.9%10.8%2.7%
Apr 202622.6%27.6%15.1%12.4%10.1%10.1%2%
May 202626.3%26.3%14.4%11.8%9.6%9.6%1.9%
Jun 202633.3%22.2%12.2%12.2%8.1%10%2%
Jul 202634.7%23.2%12.7%10.4%8.5%8.5%2.1%
Aug 202632.3%26.4%11.8%11.8%7.9%7.9%1.9%
Sep 202630.3%24.7%13.5%11.1%9.1%9.1%2.2%

How has the Benadryl and Zyrtec comparison changed over the last 12 months?

3 findings

How did search popularity change for United States allergy medicine brands in September 2026?

2 changes
  1. In September 2026, Benadryl lost share of searches among allergy medicine brands in the United States, from 32.3% to 30.3%.

  2. In September 2026, Zyrtec lost share of searches among allergy medicine brands in the United States, from 26.4% to 24.7%.

How are branded searches counted?

2 search terms

Brandwave collects information about searches that people make online using Benadryl’s and Zyrtec’s names. When viewed over time, estimated search volumes for these branded terms can be used to understand whether interest in the brands is growing, holding steady, or fading.

Benadryl

1 branded search term

  • benadryl

Zyrtec

1 branded search term

  • zyrtec

How the Brand Demand Index is measured

Other head-to-heads among allergy medicine brands

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