Host Defense vs Nootropics Depot:Which is more popular?
In October 2026, Host Defense had more branded searches than Nootropics Depot among mushroom supplement brands worldwide. Host Defense had about 9,000 branded searches, while Nootropics Depot had 350. Host Defense made up 28.8% of all mushroom supplement brand searches we track, and Nootropics Depot accounted for 1.1%. When we asked ChatGPT and Google AI Overviews about mushroom supplement brands, Nootropics Depot appeared in three of the five answers and Host Defense in one. Nootropics Depot was mentioned before Host Defense in every answer.
Who do people search for more?
Host Defense, about 26 searches for every 1 for Nootropics Depot
Who does AI mention more?
Nootropics Depot, mentioned in 3 of 5 answers, Host Defense in 1
Who does AI recommend more?
Nootropics Depot, named ahead of Host Defense in every answer
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Top mushroom supplement brands in ChatGPT and Google AI Overviews
In three ChatGPT questions and two Google AI Overviews, Nootropics Depot was mentioned in three out of five: in all three ChatGPT answers, but not in either of the two Google AI Overviews. Host Defense was mentioned in one out of five: in one of the three ChatGPT answers, but not in either of the two Google AI Overviews. Nootropics Depot was listed before Host Defense in every answer.
Most recommended by AI
Brands get a higher ranking if they are mentioned earlier in the answers.
Mentioned by AI
Each dot is one answer, filled in when that answer mentions the brand.
Real Mushrooms4 of 5Named in 3 of 3 ChatGPT answersNamed in 1 of 2 Google answers
Nootropics Depot3 of 5Named in 3 of 3 ChatGPT answersNamed in 0 of 2 Google answers
Host Defense1 of 5Named in 1 of 3 ChatGPT answersNamed in 0 of 2 Google answers
Life Cykel0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers
Om Mushrooms0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers
Genius Mushrooms0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers
SuperFeast0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers- GanoPoly0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers
- Teelixir0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers
Mushroom Revival0 of 5Named in 0 of 3 ChatGPT answersNamed in 0 of 2 Google answers
See every answer about mushroom supplement brands
5 answers
Asked ChatGPT
“Which mushroom supplement brand should I buy?”
Asked ChatGPT
“What are the best mushroom supplement brands?”
Asked ChatGPT
“What's the best lion's mane supplement brand for focus?”
Searched Google, AI Overview
“lions mane supplement”
Searched Google, AI Overview
“best mushroom supplement”
Not named in any answer:
Brands are shown in the order each answer named them. The survey took place in the United States on October 28, 2026.
Is Host Defense or Nootropics Depot more popular in search?
This chart shows how often people search Google for Host Defense and Nootropics Depot by name. Each line represents a brand's share of searches for all ten mushroom supplement brands we track, month by month, from English-language searches worldwide.
Share of searches by month for Host Defense, Nootropics Depot. The figures are in the table below the chart.
View monthly share of searches table
| Month | Real Mushrooms | Host Defense | Life Cykel | Om Mushrooms | Genius Mushrooms | SuperFeast | GanoPoly | Nootropics Depot | Teelixir | Mushroom Revival |
|---|---|---|---|---|---|---|---|---|---|---|
| Nov 2025 | 32.2% | 25.7% | 15.7% | 8.3% | 4.5% | 10.5% | 0.21% | 0.95% | 1.1% | 0.76% |
| Dec 2025 | 35.2% | 28.1% | 14.1% | 9.4% | 4.2% | 6.3% | 0.29% | 0.83% | 1% | 0.68% |
| Jan 2026 | 32% | 28.4% | 15.6% | 10.6% | 3.8% | 6.9% | 0.26% | 0.92% | 0.92% | 0.62% |
| Feb 2026 | 33.4% | 26.7% | 16.3% | 11.1% | 4% | 5.9% | 0.27% | 0.94% | 0.96% | 0.52% |
| Mar 2026 | 34.6% | 26.1% | 16% | 10.4% | 3.9% | 5.8% | 0.63% | 1.1% | 0.94% | 0.51% |
| Apr 2026 | 36.6% | 23.9% | 16.1% | 10.5% | 3.9% | 5.9% | 0.51% | 0.93% | 0.95% | 0.63% |
| May 2026 | 37% | 25% | 13.8% | 11.4% | 3.3% | 6.1% | 0.54% | 1.1% | 1.2% | 0.54% |
| Jun 2026 | 40.2% | 22.5% | 12.4% | 10.6% | 3.7% | 6.8% | 0.59% | 1.3% | 1.4% | 0.59% |
| Jul 2026 | 39.7% | 25% | 10% | 10.8% | 3.6% | 6.7% | 1.1% | 1.3% | 1.3% | 0.47% |
| Aug 2026 | 37.8% | 25.2% | 12.3% | 10.6% | 3.6% | 6.7% | 1.1% | 1.3% | 1.1% | 0.39% |
| Sep 2026 | 36.7% | 26.7% | 9.7% | 12.6% | 4.3% | 6.3% | 0.7% | 1.5% | 1.1% | 0.37% |
| Oct 2026 | 35.2% | 28.8% | 11.5% | 10% | 5.1% | 5.1% | 1.5% | 1.1% | 1% | 0.54% |
Nootropics Depot sells other things too, so only its searches that name this product count here, like “nootropics depot reishi”.
How has branded search for Host Defense and Nootropics Depot changed worldwide over the last 12 months?
3 findings
- Host Defense was ahead of Nootropics Depot in every measured month of the 12 months ending October 2026.
- Across the 12 months ending October 2026, Host Defense’s share of searches among mushroom supplement brands worldwide moved from 25.7% to 28.8%, and its estimated monthly branded searches moved from 10.8K to 9K.
- Across the 12 months ending October 2026, Nootropics Depot’s share of searches among mushroom supplement brands worldwide moved from 0.95% to 1.1%, and its estimated monthly branded searches moved from 400 to 350.
How did search popularity change for mushroom supplement brands worldwide in October 2026?
3 changes
In October 2026, GanoPoly overtook Nootropics Depot and Teelixir to rank 7th among mushroom supplement brands worldwide, with 1.5% of the searches.

In October 2026, Host Defense gained share of searches among mushroom supplement brands worldwide, from 26.7% to 28.8%.

Estimated monthly branded searches for Nootropics Depot worldwide fell 12.5% over 12 measured months, from 400 to 350 in October 2026.
How are Host Defense’s and Nootropics Depot’s branded searches counted?
5 search terms
Brandwave collects information about searches that people make online using Host Defense’s and Nootropics Depot’s names. When viewed over time, estimated search volumes for these branded terms can be used to understand whether interest in the brands is growing, holding steady, or fading.
Host Defense
2 branded search terms
- host defense
- host defense mushrooms
Nootropics Depot
3 branded search terms
- nootropics depot lions mane
- nootropics depot mushroom
- nootropics depot reishi
Other head-to-heads among mushroom supplement brands

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